Original holes in parchment pages of manuscripts seem to occur especially often in monastic manuscripts, since many monks could not afford (or did not care for) the luxury of rejecting sheets accidentally damaged in preparation. The scribe here has carefully written the text around a hole in a late twelfth-century manuscript made probably at Winchcombe Abbey in Gloucectershire

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After Christopher De Hamel, Medieval Craftsmen. Scribes and Illuminators (London: British Museum Press, 1992), pic. 6, p. 12.